= Workshop on Metabolic Modelling = == Tutors == * David Fell (DF: Oxford Brookes University) * Mark Poolman (MP: Oxford Brookes University) * Noah Mesfin (NM: Oxford Brookes University) * Ela Al-Saidi (ES: Oxford Brookes University) * Kailash Adhikari (KA) == Reading List == . A reading list for topics covered in the course is provided [[Meetings/Nepal2018/Reading|here]]. == Course Timetable and Resources == ||'''Day''' ||'''Time''' ||'''Activity''' ||'''Links''' ||'''Lecturer''' || ||'''Thursday''' ||'''AM''' || || || || ||28/06/18 ||09:00 ||Admin & Registration || || || || ||10:00 ||Opening Ceremony || || || || ||10:30 ||Introductions. Each participant introduces themself in 2-3 sentences: name, place of study/work; what they do. || ||Everyone || || ||11:00 ||Tea || || || || ||11:30 ||Welcome and introduction to the course ||[[http://mudsharkstatic.brookes.ac.uk/Nepal2018/L0.pdf|Slides]] ||DF || || ||13:00 ||Lunch || || || || ||'''PM''' || || || || || ||14:00 ||L1. Introduction to metabolic modelling. Mathematical representation of metabolic networks. Outline of the week ||[[http://mudsharkstatic.brookes.ac.uk/Nepal2018/L1.pdf|Slides]] ||DF || || || ||Tea/coffee || || || || || ||L2. Computational representation of metabolic networks ||[[http://mudsharkstatic.brookes.ac.uk/Nepal2018/L2.pdf|Slides]] ||MP || || || ||P1. Computers: checking internet connectivity, software installation. ||[[Meetings/Nepal2018/ScrumPyInstall|Installation]] of !ScrumPy. ||All || || ||!6:45 ||Close || || || ||'''Friday''' ||'''AM''' || || || || || ||09:30 ||L3. Null space and elementary modes ||[[http://mudsharkstatic.brookes.ac.uk/Nepal2018/L3.pdf|Slides]] ||NM || || || ||Demo for Prac 2. || ||TBC || || || ||P2. Python and !ScrumPy (Part 1) ||[[Meetings/Nepal2018/Prac2|Prac2]] ||All || || ||11:00 ||Break || || || || || ||P2. Python and !ScrumPy (Part 2) ||[[Meetings/Nepal2018/Prac2|Prac2]] ||All || || ||13:00 ||Lunch || || || || ||'''PM''' ||L3b. Examples of Elementary Modes Analysis ||[[http://mudsharkstatic.brookes.ac.uk/Nepal2018/L3b.pdf|Slides]] ||DF || || || ||L4. Biotechnological applications of metabolic network analysis ||[[http://mudsharkstatic.brookes.ac.uk/Nepal2018/L4.pdf|Slides]] ||DF || || || ||Demo for Prac 3 || ||TBC || || || ||P3. Models, kernels, subsets and elementary modes ||[[Meetings/Nepal2018/Prac3|Prac 3]] ||All || || || ||Break || || || || || ||P3. Models, kernels, subsets and elementary modes (continued) || ||All || || ||16:45 ||Close || || || ||'''Monday''' || || || || || || ||09:30 ||Demo for Prac4 || ||MP || || || ||P4. Structural analysis of the Calvin Cycle. ||[[Meetings/Nepal2018/Prac4|Prac 4]] ***instructions ||ALL || || ||11:00 ||Break || || || || || ||L5. Linear Programming and Flux Balance Analysis ||[[http://mudsharkstatic.brookes.ac.uk/Nepal2018/L5.pdf|Slides]] ||NM || || || ||L6. Sources of data for metabolic models ||[[http://mudsharkstatic.brookes.ac.uk/Nepal2018/L6.pdf|Slides]] ||DF || || ||13:00 ||Lunch || || || || ||'''PM''' ||L7. The unique metabolism of ''Acetobacterium woodii'' ||[[http://mudsharkstatic.brookes.ac.uk/Nepal2018/L7.pdf|Slides]] [[Meetings/Nepal2018/ScrumPy_demo|ScrumPy_demo]] ||NM || || || ||P5. Flux Balance Analysis of alkane biosynthesis in ''E coli''. ||[[Meetings/Nepal2018/Prac5|Prac 5]] ||All || || ||16:45 ||close || || || ||'''Tuesday''' ||'''AM''' || || || || || ||09:30 ||L8. '''a''': Summary of Null-space and linear programming approaches '''b''': Practical applications of LP ||[[http://mudsharkstatic.brookes.ac.uk/Nepal2018/L8.pdf|Slides]]; [[http://mudsharkstatic.brookes.ac.uk/Nepal2018/L4b.pdf|Slides]] ||MP, DF || || || ||P5 Flux Balance Analysis of alkane biosynthesis in ''E coli''. ||[[Meetings/Nepal2018/Prac5|Prac 5]] || || || ||11:00 ||Break || || || || || ||Practical 5 continues || || || || ||13:00 ||Lunch || || || || ||14:00 ||L9 Modelling photosynthesis in eukaryotes. ||[[http://mudsharkstatic.brookes.ac.uk/Nepal2018/L9.pdf|Slides]]||KA || || || ||L10 Beyond structural modelling || ||EA || || || ||Closing and Presentation of Certificates || || || || ||16:45 ||Depart || || ||