= Metabolic Modelling: Tools, Techniques, and Applications in Research = == India 2024 == == Tutors == * Dr Mark Poolman (MP: Oxford Brookes University) * Dr Anu Raghunathan (AR: NCL, Pune) * Dr Dipali Singh (DS: Quadram Institute, Norwich) * Pareena Verma (PV: Oxford Brookes University) * Dr Trunil Desai (TD: Oxford Brookes University) == Guest Speaker == * Prof. Sundip Kundu (SK: University of Calcutta) == Course Timetable and Resources == ||'''Day''' ||'''Time''' ||'''Activity''' ||'''Links''' ||'''Tutor''' || ||Day 1 - Tues(17/09) || || || || || ||PM ||12:00 ||Arrival, Admin & Registration etc || || || || ||12:30 ||Lunch || || || || ||14:30 ||Welcome and introduction to the course - why do modelling? || ||MP/ AR || || ||14:30 ||Lecture 1: Introduction to metabolic modelling. ||[[http://mudsharkstatic.brookes.ac.uk/India2024/L1.pdf|Slides]] ||PV/TD || || ||15:00 ||Lecture 2: Python and computational representation of metabolic networks. ||[[http://mudsharkstatic.brookes.ac.uk/India2024/L2.pdf|Slides]] ||TD || || ||15:30 ||Tea/Coffee Break || || || || ||15:45 ||P1. Computers: checking internet connectivity, software installation. ||[[https://mudshark.brookes.ac.uk/Meetings/India2024/ScrumPyInstall|Prac1]] ||All || || || ||P2. Python and [[https://mudshark.brookes.ac.uk/ScrumPy|ScrumPy]] ||[[https://mudshark.brookes.ac.uk/Meetings/India2024/Prac2|Prac2]] ||All || || || ||Close || || || || || || || || || ||Day 2 - Wed (18/09) || || || || || ||AM ||09:00 ||Lecture 3: Null space, elementary modes and conserved cycles ||[[http://mudsharkstatic.brookes.ac.uk/Barcelona2023/L3.pdf|Slides]] ||TD || || ||10:00 ||Lecture 4. Linear programming, Flux Balance Analysis and Applications ||[[http://mudsharkstatic.brookes.ac.uk/India2024/L4.pdf|Slides]] ||AR || || ||11:00 ||P3. Null space, subsets and elementary modes ||[[https://mudshark.brookes.ac.uk/Meetings/India2024/Prac3|Prac3]] ||All || ||PM ||12:30 ||Lunch || || || || ||14:30 ||Constraint-based modelling of C3, C4 and CAM || ||SK || || ||15:30 ||Tea/Coffee Break || || || || ||15:45 ||P4: Linear programming and Flux Balance Analysis ||[[http://mudsharkstatic.brookes.ac.uk/Barcelona2023/P4|Prac4]] || || || || || || || || ||Day 3 Thurs (19/09) || || || || || ||AM ||9:00 ||P4: Continued || || || || ||10:00 ||Lecture 5: Determination of minimal media requirements for Campylobacter jejuni ||[[http://mudsharkstatic.brookes.ac.uk/India2024/L8.pdf|Slides]] ||DS || || ||11:00 ||P5: Determination of minimal media requirements for ''Campylobacter jejuni'' ||[[https://mudsharkstatic.brookes.ac.uk/Nottingham2022/P5|Prac5]] ||All || ||PM ||12:30 ||Lunch || || || || ||14:30 ||Lecture 6: Antimicrobial target identification by GSMM - INNOTARGETS ||[[http://mudsharkstatic.brookes.ac.uk/India2024/L7.pdf|Slides]] ||PV/MP || || ||15:30 ||Tea/Coffee Break || || || || ||15:45 ||P6: Antimicrobial target identification by GSMM - INNOTARGETS ||[[http://mudsharkstatic.brookes.ac.uk/India2024/P5_instructions.pdf|Prac6]] [[http://mudsharkstatic.brookes.ac.uk/India2024/P5_tar.tar|Materials]] ||All || ||Day 4 - Fri (20/09) || || || || || ||AM ||09:00 ||Finish Practicals/General Discussion || ||All || || || ||Go Home! || || ||