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| This is an activity of the collaborative project [[UKIPA|Development of Metabolic Models to Support Systems Biology Approaches to Bioenergy Research]] | |
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| == About the Workshop == Why here? Why now? [[attachment:intro.pdf|Download]] some introductory slides (pdf). |
'''ICGEB, 7-11 October 2013''' |
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| This second workshop will cover kinetic modelling of metabolism and Metabolic Control Analysis, with an emphasis on their application to biotechnology and metabolic engineering. | This was an activity of the collaborative project [[UKIPA|Development of Metabolic Models to Support Systems Biology Approaches to Bioenergy Research]] |
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| == Practical Sessions == Participants are invited to bring their own laptops to the practicals to supplement the available computing resources. |
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| === Software Requirements === If you can bring a laptop, please follow [[Meetings/Riga2013/Practicals/ScrumPyVM|these instructions]] to install ScrumPy on it before the workshop. If the files are too large for Windows users to download, at least try installing the !VirtualBox software, and we will supply the ScrumPy virtual machine file at the workshop on USB memory sticks. We will also use the [[http://gnuplot.info/|GnuPlot]] plotting package; this is included with the ScrumPy virtual machine, but Windows users can download it from [[http://sourceforge.net/projects/gnuplot/files/gnuplot/4.6.3/|this site]], choosing the 'gp463-win32-setup.exe' option. |
The [[/Programme|programme and instructions]] are now on their own page. |
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| === Model Files === The model files we will be using, and referred to in the instructions below, can be found [[http://mudsharkstatic.brookes.ac.uk/Delhi2013/Models/|here.]] |
== Workshop Group Photos == |
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| == Provisional Timetable == ==== Student Contributions ==== The last hour of the first four morning sessions will be given over to student presentations. Students will be informed later as to the exact timetabling of their talks. |
{{attachment:Group1_small.jpg|alt Group photo1|width=600}} |
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| ==== Typical daily timetable ==== Mornings, 9:30 -12:30 (Monday 10:00 - 12:30); Lunch 12:30 - 14:00; Afternoons, 14:00 - 17:00 (at the latest) ||'''Time''' ||'''Activity''' ||'''Who''' || ||Mon 7th, AM ||[[Meetings/Delhi2013/Lectures/Session1|Session 1]]: Revision of mathematical representation of metabolic networks. Enzyme kinetics for modelling ||David Fell; Mark Poolman || ||Mon 7th, PM ||[[Meetings/Delhi2013/Practicals/Practical_1|Practical 1]]: Plotting enzyme kinetic functions; graphical soluton to a two enzyme system; rough time course calculation for an enzyme-catalysed reaction ||David Fell; Mark Poolman || ||Tue 8th, AM ||Session 2: [[http://mudsharkstatic.brookes.ac.uk/Delhi2013/Slides/Tues_am_Mark.pdf | Building kinetic models with ScrumPy||David Fell; Mark Poolman || ||Tue 8th, PM ||[[Meetings/Delhi2013/Practicals/Practical_2|Practical 2]]: Brief Python introduction; kinetic modelling with {{{ScrumPy}}} ||David Fell; Mark Poolman || ||Wed 9th, AM ||[[Meetings/Delhi2013/Lectures/Session3|Session 3]]: Metabolic control analysis - understanding the control of metabolic fluxes and metabolite concentrations ||David Fell; Mark Poolman || ||Wed 9th, PM ||[[Meetings/Delhi2013/Practicals/Practical_3|Practical 3]]: Kinetic modelling with {{{ScrumPy}}} continued, plus calculation of control coefficients ||David Fell; Mark Poolman || ||Thu 10th, AM ||[[Meetings/Delhi2013/Lectures/Session4|Session 4]]: Implications of metabolic control analysis for feedback inhibtion and enzyme over-expression. Case studies in biotechnology and metabolic engineering. ||David Fell; Mark Poolman || ||Thu 10th, PM ||[[Meetings/Delhi2013/Practicals/Practical_4|Practical 4]]: Simulation of pathway optimisation. Close and presentation of certificates ||David Fell; Mark Poolman || |
{{attachment:Group2_small.jpg|alt Group photo2|width=600}} |
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| Full quality versions of these can be downloaded: [[attachment:Group1.jpg|group photo 1]] and [[attachment:Group2.jpg|group photo 2]] Not exactly on the workshop timetable, but see if you can spot two of us [[https://www.facebook.com/nagalandk?rf=123263314424845|here]] (October 12th compilation). |
Delhi Workshop on Metabolic Modelling 2013
ICGEB, 7-11 October 2013
This was an activity of the collaborative project Development of Metabolic Models to Support Systems Biology Approaches to Bioenergy Research
The programme and instructions are now on their own page.
Workshop Group Photos
Full quality versions of these can be downloaded: group photo 1 and group photo 2
Not exactly on the workshop timetable, but see if you can spot two of us here (October 12th compilation).