Day

Time

Activity

Links

Lecturer

Tuesday

AM

03/04/22

09:00

Arrival, Admin & Registration

PM

13:00

Lunch

'

???

Introductions. Each participant introduces themself in 2-3 sentences: name, place of study/work; what they do.

?? Do this or similar ??

Everyone

Welcome and introduction to the course. Outline of the week

Slides

DF

14:00

L1. Introduction to metabolic modelling. Mathematical representation of metabolic networks.

Slides

DF

Tea/coffee

L2. Computational representation of metabolic networks

Slides

MP

P1. Computers: checking internet connectivity, software installation.

Installation of ScrumPy.

All

Close

Wednesday

AM

09:30

L3. Null space and elementary modes

Slides

NP

Demo for Prac 2.

MP

P2. Python and ScrumPy (Part 1)

Prac2

All

11:00

Break

P2. Python and ScrumPy (Part 2)

Prac2

All

13:00

Lunch

PM

L3b. Examples of Elementary Modes Analysis

Slides

DF

L4. Biotechnological applications of metabolic network analysis

Slides

DF

Demo for Prac 3

TBC

P3. Models, kernels, subsets and elementary modes

Prac 3

All

Break

P3. Models, kernels, subsets and elementary modes (continued)

All

16:45

Close

Thursday

09:30

Demo for Prac4

MP

P4. Structural analysis of the Calvin Cycle.

Prac 4 ***instructions

ALL

11:00

Break

L5. Linear Programming and Flux Balance Analysis

Slides

NM

L6. Sources of data for metabolic models

Slides

DF

13:00

Lunch

PM

L7. The unique metabolism of Acetobacterium woodii

Slides ScrumPy_demo

NM

P5. Flux Balance Analysis of alkane biosynthesis in E coli.

Prac 5

All

16:45

close

Friday

AM

09:30

L8. a: Summary of Null-space and linear programming approaches b: Practical applications of LP

Slides; Slides

MP, DF

P5 Flux Balance Analysis of alkane biosynthesis in E coli.

Prac 5

11:00

Break

Practical 5 continues

13:00

Lunch

Conclusions