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Innotargets: Introduction to Metabolic Modelling

India 2024

Tutors

Guest Speaker

TBD

Day

Time

Activity

Links

Tutor

Day 1 – Monday





AM

09:30:00

Arrival, Admin etc



10:00:00

Welcome and introduction to the course - why do modelling?

MP

10:30:00

Lecture 1: Introduction to metabolic modelling.

Slides

PV/TD

Lecture 2: Python and computational representation of metabolic networks.

Slides

TD

P1. Computers: checking internet connectivity, software installation.

Prac1

All


12:00:00

Lunch



PM

13:00:00

P1. Contd.


All


13:30:00

P2. Python and ScrumPy

Prac2

All


17:00:00

Close



Day 2 – Tuesday





AM

10:00:00

Lecture 3: Null space, elementary modes and conserved cycles

Slides

MP



P3. Null space, subsets and elementary modes

Prac3

All


12:00:00

Lunch



PM

13:00:00

Lecture 4: Linear programming and Flux Balance Analysis

Slides

MP



P4. LP – Central metabolism of Staphylococcus epidermidis

Prac4

All


17:00:00

Close



Day 3 – Wednesday

AM

10:00:00

Lecture 5: Construction, Validation and Applications of GSMs


DS


11:00:00

Lecture 6: Antimicrobial target identification by GSMM - INNOTARGETS


PV/MP



Lunch



PM

13:00:00

P5: Antimicrobial target identification by GSMM - INNOTARGETS


All


15:00:00

Group discussion: Please form a group of 4-5 to discuss project ideas where metabolic modelling can be applied.


All


17:00:00

Close








Day 4 – Thursday





AM

10:00:00

Participants to present the outcome of the group discussion


All



Lunch



PM

13:00:00

Lecture 7: Determination of minimal media requirements for Campylobacter jejuni


DS


14:00:00

P6: Determination of minimal media requirements for Campylobacter jejuni


All


17:00:00

Close