Innotargets: Introduction to Metabolic Modelling
Barcelona 2023
Tutors
- Mark Poolman (MP: Oxford Brookes University)
- Oliver Ebenhoeh (OE: Heinrich Heine University, Dusseldorf)
- Yanica Said (YS: Oxford Brookes University)
- Dipali Singh (DS: Quadram Institute, Norwich)
Guest Speaker
- Dr. Rodriguez-Caso (University of Malaga)
Course Timetable and Resources
Day |
Time |
Activity |
Links |
Lecturer |
30/05/23 Tuesday |
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AM |
09:00 |
Arrival, Admin & Registration Hotel check-in etc |
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13:00 |
Lunch |
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PM |
14:00 |
Welcome and introduction to the course - why do modelling? |
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MP |
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Lecture 1: Introduction to metabolic modelling. Mathematical representation of metabolic networks. |
YS |
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15:30 |
Tea/coffee |
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Lecture 2: Python and computational representation of metabolic networks. |
MP |
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P1. Computers: checking internet connectivity, software installation. |
All |
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P2. Python and ScrumPy |
All |
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1800 |
Close |
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Wednesday |
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AM |
09:00 |
Lecture 3: Null space, elementary modes and conserved cycles |
OE |
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P3. Null space, subsets and elementary modes |
All |
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10:30 |
tea/coffee |
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P3 continues |
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13:00 |
Lunch |
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PM |
14:00 |
Guest lecture - Synthetic Biology: Uncovering principles of biological design applying math and experiments. |
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Dr. Rodriguez-Caso |
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15:00 |
Depart social activity |
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All |
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Thursday |
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AM |
09:00 |
Lecture 4. Linear programming and Flux Balance Analysis |
OE |
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Lecture 5: Response to varying ATP demand in a metabolic model of Salmonella typhimurium |
MP |
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10:30 |
Break |
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P4 Central metabolism of S. epidermidis |
YS/DS |
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13:00 |
Lunch |
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Lecture 6: Determination of minimal media requirements for Campylobacter jejuni |
DS |
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P5: Determination of minimal media requirements for Campylobacter jejuni |
All |
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Friday |
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AM |
09:00 |
Lecture 7: construction and validation |
DS |
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Finish practicals/General discussion/Something else |
(Optional if time allows) |
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13:00 |
Lunch |
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Go home! |
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